Although gentamicin is highly active against Rhodococcus equi in vitro, its clinical efficacy has been limited presumably due to poor cellular uptake. Encapsulation of drugs in liposomes enhances their cellular uptake.

… Findings clearly indicate that NDS27 reduces the systemic and alveolar activation of neutrophils induced by LPS inhalation.

The aim of the study was to test the effects of inhalation with the modified highly soluble curcumin derivate NDS27 (World Intellectual Property Organization 2009), on clinical signs, broncho-alveolar lavage fluids (BALF) cytology, and lung function in RAO-affected horses.

This filly was again examined by endoscope by Dr. Latson, and digital copies of the lesion were taken on Oct 1, 2012 (Fig #1.) for a baseline to assess the treatment protocol that was instituted on Oct 2, 2012.