The amount and distribution of the uptake gives you an indication of how that specific organ is functioning. In the case with the Flexineb, it was important to demonstrate how well the nebulizer can deliver medication to the lower airway.

From the perspective of published work thus far, there is evidence that HA may exert a protective effect against injury in a number of respiratory diseases. HA prevents elastin injury by elastases in vivo in hamster models of pulmonary emphysema and in vitro in elastin matrices.

To compare concentrations of desfuroylceftiofur acetamide (DCA) in plasma and pulmonary epithelial lining fluid (PELF) of foals after nebulisation or i.m. administration of ceftiofur sodium and to determine if nebulisation of ceftiofur sodium induces airway inflammation.

An aerosol is a suspension of liquid or solid particles dispersed in gas. The physical characteristics of the particles, including size, hydrophobicity, and shape, affect their ability to travel within the airways. The size of the particles is regarded as one of the most critical physical characteristics of aerosol therapy.

The aim of the study was to find out if, and to what extent, our patient could be helped on a sustainable basis using regular inhalation carried out by a Flexineb inhaler.

These data indicate a relationship between HA levels, local inflammation and severity of disease, and suggest enhanced breakdown of HA in the lungs of patients with COPD.

The aim of the study was to find out if, and to what extent, our patient could be helped on a sustainable basis using regular inhalation carried out by a Flexineb inhaler.

Although gentamicin is highly active against Rhodococcus equi in vitro, its clinical efficacy has been limited presumably due to poor cellular uptake. Encapsulation of drugs in liposomes enhances their cellular uptake.

… Findings clearly indicate that NDS27 reduces the systemic and alveolar activation of neutrophils induced by LPS inhalation.